What these duos unlock
Nautilus performs best when allies extend the first window of control or damage. The strongest pairings on this page, such as Kai'Sa, Jinx, Miss Fortune, create cleaner fights and more reliable tempo swings.
Synergies
Nautilus excels in burst compositions that leverage his long CC chain to eliminate locked targets. He benefits from allies who can convert his immobilizes into immediate kills. Multi-engage or dive compositions get the maximum from his lockdown capability.
Dredge Line→
Riptide→
Killer Instinct→
Depth Charge→
Void Seeker
Dredge Line→
Riptide→
Flame Chompers!→
Depth Charge→
Super Mega Death Rocket!
Dredge Line→
Depth Charge→
Bullet Time
Dredge Line→
Relentless Pursuit→
Piercing Light→
Riptide
Dredge Line→
Stand Aside→
Spinning Axes→
Depth ChargeNautilus performs best when allies extend the first window of control or damage. The strongest pairings on this page, such as Kai'Sa, Jinx, Miss Fortune, create cleaner fights and more reliable tempo swings.
Nautilus has a support profile, so allies with Engage, CC Chain are usually the best fit. You often get the most value from partners played in ADC.
These pairings matter most around first engage timing, objective setup, and follow-up on crowd control. The page is not just naming allies: it highlights combinations that reduce execution risk for Nautilus.
Kai'Sa is one of the strongest partners highlighted on this page because the duo creates cleaner engage or follow-up sequences for Nautilus.
Nautilus usually gains the most from allies who bring Engage. The goal is to make the first action easier to convert into damage, tempo, or objective control.
Strong duos such as Kai'Sa or Jinx matter, but not more than champion mastery. Use these synergies to refine a good draft, not to replace a pick you cannot execute.